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Colorcon Inc hypromellose (hpmc, methocel® k15m)
Hypromellose (Hpmc, Methocel® K15m), supplied by Colorcon Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/hypromellose (hpmc, methocel® k15m)/product/Colorcon Inc
Average 90 stars, based on 1 article reviews
hypromellose (hpmc, methocel® k15m) - by Bioz Stars, 2026-03
90/100 stars

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Schematic of the floating matrix tablet prepared by the sublimation technique ( a ). The gelatinous barrier of the hydrated hydroxypropyl methylcellulose (HPMC) leads to air entrapment and retards the drug release ( b ).

Journal: Gels

Article Title: Design and Evaluation of New Gel-Based Floating Matrix Tablets Utilizing the Sublimation Technique for Gastroretentive Drug Delivery

doi: 10.3390/gels10090581

Figure Lengend Snippet: Schematic of the floating matrix tablet prepared by the sublimation technique ( a ). The gelatinous barrier of the hydrated hydroxypropyl methylcellulose (HPMC) leads to air entrapment and retards the drug release ( b ).

Article Snippet: Hydroxypropyl methylcellulose (HPMC) (Methocel ® E15LV, K100LV, K4M, and K15M; Dow Chemical, Midland, MI, USA) served as the gel-forming polymer for the tablets.

Techniques: Sublimation

Physical characteristics of the floating matrix tablets after drying by incubation at 70 °C for 72 h.

Journal: Gels

Article Title: Design and Evaluation of New Gel-Based Floating Matrix Tablets Utilizing the Sublimation Technique for Gastroretentive Drug Delivery

doi: 10.3390/gels10090581

Figure Lengend Snippet: Physical characteristics of the floating matrix tablets after drying by incubation at 70 °C for 72 h.

Article Snippet: Hydroxypropyl methylcellulose (HPMC) (Methocel ® E15LV, K100LV, K4M, and K15M; Dow Chemical, Midland, MI, USA) served as the gel-forming polymer for the tablets.

Techniques: Incubation

Floating properties of the floating matrix tablets.

Journal: Gels

Article Title: Design and Evaluation of New Gel-Based Floating Matrix Tablets Utilizing the Sublimation Technique for Gastroretentive Drug Delivery

doi: 10.3390/gels10090581

Figure Lengend Snippet: Floating properties of the floating matrix tablets.

Article Snippet: Hydroxypropyl methylcellulose (HPMC) (Methocel ® E15LV, K100LV, K4M, and K15M; Dow Chemical, Midland, MI, USA) served as the gel-forming polymer for the tablets.

Techniques:

Effect of the grade of HPMC on the floating force ( a ) and theophylline released ( b ) from floating matrix tablets (30% w / w menthol) in 0.1 N HCl.

Journal: Gels

Article Title: Design and Evaluation of New Gel-Based Floating Matrix Tablets Utilizing the Sublimation Technique for Gastroretentive Drug Delivery

doi: 10.3390/gels10090581

Figure Lengend Snippet: Effect of the grade of HPMC on the floating force ( a ) and theophylline released ( b ) from floating matrix tablets (30% w / w menthol) in 0.1 N HCl.

Article Snippet: Hydroxypropyl methylcellulose (HPMC) (Methocel ® E15LV, K100LV, K4M, and K15M; Dow Chemical, Midland, MI, USA) served as the gel-forming polymer for the tablets.

Techniques:

Percentage water uptake ( a ) and percentage erosion ( b ) of different HPMC viscosity grades of the floating matrix tablets (30% w / w menthol) in 0.1 N HCl.

Journal: Gels

Article Title: Design and Evaluation of New Gel-Based Floating Matrix Tablets Utilizing the Sublimation Technique for Gastroretentive Drug Delivery

doi: 10.3390/gels10090581

Figure Lengend Snippet: Percentage water uptake ( a ) and percentage erosion ( b ) of different HPMC viscosity grades of the floating matrix tablets (30% w / w menthol) in 0.1 N HCl.

Article Snippet: Hydroxypropyl methylcellulose (HPMC) (Methocel ® E15LV, K100LV, K4M, and K15M; Dow Chemical, Midland, MI, USA) served as the gel-forming polymer for the tablets.

Techniques: Viscosity

Mathematic modeling and drug release kinetics of theophylline from the floating matrix tablets.

Journal: Gels

Article Title: Design and Evaluation of New Gel-Based Floating Matrix Tablets Utilizing the Sublimation Technique for Gastroretentive Drug Delivery

doi: 10.3390/gels10090581

Figure Lengend Snippet: Mathematic modeling and drug release kinetics of theophylline from the floating matrix tablets.

Article Snippet: Hydroxypropyl methylcellulose (HPMC) (Methocel ® E15LV, K100LV, K4M, and K15M; Dow Chemical, Midland, MI, USA) served as the gel-forming polymer for the tablets.

Techniques: Diffusion-based Assay

Effect of the type of sublimation substance on the floating force of the floating matrix tablets (HPMC K15M) in 0.1 N HCl.

Journal: Gels

Article Title: Design and Evaluation of New Gel-Based Floating Matrix Tablets Utilizing the Sublimation Technique for Gastroretentive Drug Delivery

doi: 10.3390/gels10090581

Figure Lengend Snippet: Effect of the type of sublimation substance on the floating force of the floating matrix tablets (HPMC K15M) in 0.1 N HCl.

Article Snippet: Hydroxypropyl methylcellulose (HPMC) (Methocel ® E15LV, K100LV, K4M, and K15M; Dow Chemical, Midland, MI, USA) served as the gel-forming polymer for the tablets.

Techniques: Sublimation

Percentage water uptake ( a ) and percentage erosion ( b ) for the floating matrix tablets (HPMC E15LV) with different types of sublimation substances in 0.1 N HCl.

Journal: Gels

Article Title: Design and Evaluation of New Gel-Based Floating Matrix Tablets Utilizing the Sublimation Technique for Gastroretentive Drug Delivery

doi: 10.3390/gels10090581

Figure Lengend Snippet: Percentage water uptake ( a ) and percentage erosion ( b ) for the floating matrix tablets (HPMC E15LV) with different types of sublimation substances in 0.1 N HCl.

Article Snippet: Hydroxypropyl methylcellulose (HPMC) (Methocel ® E15LV, K100LV, K4M, and K15M; Dow Chemical, Midland, MI, USA) served as the gel-forming polymer for the tablets.

Techniques: Sublimation

Effect of the amounts of sublimation substances on the floating force of floating matrix tablets (HPMC K15M) in 0.1 N HCl: ( a ) menthol; ( b ) ammonium carbonate.

Journal: Gels

Article Title: Design and Evaluation of New Gel-Based Floating Matrix Tablets Utilizing the Sublimation Technique for Gastroretentive Drug Delivery

doi: 10.3390/gels10090581

Figure Lengend Snippet: Effect of the amounts of sublimation substances on the floating force of floating matrix tablets (HPMC K15M) in 0.1 N HCl: ( a ) menthol; ( b ) ammonium carbonate.

Article Snippet: Hydroxypropyl methylcellulose (HPMC) (Methocel ® E15LV, K100LV, K4M, and K15M; Dow Chemical, Midland, MI, USA) served as the gel-forming polymer for the tablets.

Techniques: Sublimation

Composition of the tablet models and production parameters.

Journal: Polymers

Article Title: Polymer Tablet Matrix Systems for the Controlled Release of Dry Betula pendula Leaf Extract

doi: 10.3390/polym15173558

Figure Lengend Snippet: Composition of the tablet models and production parameters.

Article Snippet: Hydroxypropyl methylcellulose of different molecular weights (Methocel K100M, Methocel K15M and Methocel K4M (hydroxypropyl methylcellulose) was purchased from The Dow Chemical Company (Midland, MI, USA).

Techniques:

Levels of variation of the independent variables.

Journal: Polymers

Article Title: Polymer Tablet Matrix Systems for the Controlled Release of Dry Betula pendula Leaf Extract

doi: 10.3390/polym15173558

Figure Lengend Snippet: Levels of variation of the independent variables.

Article Snippet: Hydroxypropyl methylcellulose of different molecular weights (Methocel K100M, Methocel K15M and Methocel K4M (hydroxypropyl methylcellulose) was purchased from The Dow Chemical Company (Midland, MI, USA).

Techniques: Molecular Weight

Tablet models and levels of coding in the 3 3 full factorial design.

Journal: Polymers

Article Title: Polymer Tablet Matrix Systems for the Controlled Release of Dry Betula pendula Leaf Extract

doi: 10.3390/polym15173558

Figure Lengend Snippet: Tablet models and levels of coding in the 3 3 full factorial design.

Article Snippet: Hydroxypropyl methylcellulose of different molecular weights (Methocel K100M, Methocel K15M and Methocel K4M (hydroxypropyl methylcellulose) was purchased from The Dow Chemical Company (Midland, MI, USA).

Techniques: Molecular Weight

Hyperoside release profiles from models F1–F9, EC/HPMC ratio 40/60 ( n = 3).

Journal: Polymers

Article Title: Polymer Tablet Matrix Systems for the Controlled Release of Dry Betula pendula Leaf Extract

doi: 10.3390/polym15173558

Figure Lengend Snippet: Hyperoside release profiles from models F1–F9, EC/HPMC ratio 40/60 ( n = 3).

Article Snippet: Hydroxypropyl methylcellulose of different molecular weights (Methocel K100M, Methocel K15M and Methocel K4M (hydroxypropyl methylcellulose) was purchased from The Dow Chemical Company (Midland, MI, USA).

Techniques:

Hyperoside release profiles from models F10–F18, EC/HPMC ratio 25/75 ( n = 3).

Journal: Polymers

Article Title: Polymer Tablet Matrix Systems for the Controlled Release of Dry Betula pendula Leaf Extract

doi: 10.3390/polym15173558

Figure Lengend Snippet: Hyperoside release profiles from models F10–F18, EC/HPMC ratio 25/75 ( n = 3).

Article Snippet: Hydroxypropyl methylcellulose of different molecular weights (Methocel K100M, Methocel K15M and Methocel K4M (hydroxypropyl methylcellulose) was purchased from The Dow Chemical Company (Midland, MI, USA).

Techniques:

Hyperoside release profiles from models F19–F27, EC/HPMC ratio 10/90 ( n = 3).

Journal: Polymers

Article Title: Polymer Tablet Matrix Systems for the Controlled Release of Dry Betula pendula Leaf Extract

doi: 10.3390/polym15173558

Figure Lengend Snippet: Hyperoside release profiles from models F19–F27, EC/HPMC ratio 10/90 ( n = 3).

Article Snippet: Hydroxypropyl methylcellulose of different molecular weights (Methocel K100M, Methocel K15M and Methocel K4M (hydroxypropyl methylcellulose) was purchased from The Dow Chemical Company (Midland, MI, USA).

Techniques:

Tukey’s test—hydrophobic/hydrophilic polymer  (EC/HPMC).

Journal: Polymers

Article Title: Polymer Tablet Matrix Systems for the Controlled Release of Dry Betula pendula Leaf Extract

doi: 10.3390/polym15173558

Figure Lengend Snippet: Tukey’s test—hydrophobic/hydrophilic polymer (EC/HPMC).

Article Snippet: Hydroxypropyl methylcellulose of different molecular weights (Methocel K100M, Methocel K15M and Methocel K4M (hydroxypropyl methylcellulose) was purchased from The Dow Chemical Company (Midland, MI, USA).

Techniques: Polymer

Tukey’s test—molecular weight.

Journal: Polymers

Article Title: Polymer Tablet Matrix Systems for the Controlled Release of Dry Betula pendula Leaf Extract

doi: 10.3390/polym15173558

Figure Lengend Snippet: Tukey’s test—molecular weight.

Article Snippet: Hydroxypropyl methylcellulose of different molecular weights (Methocel K100M, Methocel K15M and Methocel K4M (hydroxypropyl methylcellulose) was purchased from The Dow Chemical Company (Midland, MI, USA).

Techniques: Molecular Weight

Effect of EC/HPMC ratio and HPMC molecular weight at: ( A ) 1 t compression force (Factor C level 1); ( B ) 1.5 t compression force (Factor C level 0); and ( C ) 2 t compression force (Factor C level 1).

Journal: Polymers

Article Title: Polymer Tablet Matrix Systems for the Controlled Release of Dry Betula pendula Leaf Extract

doi: 10.3390/polym15173558

Figure Lengend Snippet: Effect of EC/HPMC ratio and HPMC molecular weight at: ( A ) 1 t compression force (Factor C level 1); ( B ) 1.5 t compression force (Factor C level 0); and ( C ) 2 t compression force (Factor C level 1).

Article Snippet: Hydroxypropyl methylcellulose of different molecular weights (Methocel K100M, Methocel K15M and Methocel K4M (hydroxypropyl methylcellulose) was purchased from The Dow Chemical Company (Midland, MI, USA).

Techniques: Molecular Weight

Tests of correlations between the technological parameters.

Journal: Polymers

Article Title: Polymer Tablet Matrix Systems for the Controlled Release of Dry Betula pendula Leaf Extract

doi: 10.3390/polym15173558

Figure Lengend Snippet: Tests of correlations between the technological parameters.

Article Snippet: Hydroxypropyl methylcellulose of different molecular weights (Methocel K100M, Methocel K15M and Methocel K4M (hydroxypropyl methylcellulose) was purchased from The Dow Chemical Company (Midland, MI, USA).

Techniques: Molecular Weight